#48 Pain

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Kim interviews Michael Hildebrand about the topic of pain. Does everyone experience pain the same way? Why do we experience pain? Is there such a thing as good pain? Discover the answers to these questions and many more, on this episode of Minding the Brain!

Dr. Michael Hildebrand completed his PhD in Molecular and Cellular Neuroscience in 2008 at the University of British Columbia. He did an industrial postdoctoral fellowship at Zalicus Pharmaceuticals in Vancouver from 2008 to 2010 followed by an academic postdoctoral fellowship at the Sick Kids Hospital in Toronto from 2010 to 2013. Dr. Hildebrand began his research lab at Carleton University in 2013. He’s also an avid runner and loves candy!

Explore Further:

Dedek A, Xu J, Kandegedara C, Lorenzo LE, Godin AG, De Konick Y, Lombroso PJ, Tai EC, Hildebrand ME. (2019) Loss of STEP61 couples disinhibition to N-methyl-D-aspartate receptop potentiation in rodent and human spinal pain processing. Brain, Volume 142, Issue 6, Pages 1535-1546.

Hildebrand ME, Xu J, Dedek A, Li Y, Sengar AS, Beggs S, Lombroso PJ, Salter MW. (2016) Potentiation of synaptic GluN2B NMDAR currents by Fyn Kinase is gated through BDNF-mediated disinhibition in spinal pain processing. Cell Reports, 17(10):2753-65.

Bourinet E, Altier C, Hildebrand ME, Trang T, Slater MW, Zamponi GW. (2014) Calcium permeable ion channels in pain signalling. Physiological Reviews 94(1): 81-140.